3l0h

X-ray diffraction
2.13Å resolution

Crystal Structure Analysis of W21A mutant of human GSTA1-1 in complex with S-hexylglutathione

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08263 (Residues: 1-222; Coverage: 100%)
Gene name: GSTA1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTX 2 x GTX
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: C2
Unit cell:
a: 100.229Å b: 94.98Å c: 51.987Å
α: 90° β: 92.63° γ: 90°
R-values:
R R work R free
0.174 0.17 0.233
Expression system: Escherichia coli BL21(DE3)