› 3kw6

X-ray diffraction
2.1Å resolution

Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A

Released:
DOI: 10.2210/pdb3kw6/pdb
PDB entry 3kw6 coloured by chain, front view.
PDB entry 3kw6 coloured by chain, side view.
PDB entry 3kw6 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Seetharaman J, Su M, Wang D, Janjua H, Cunningham K, Owens L, Xiao R, Liu J, Baran MC, Acton TB, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158589 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
26S proteasome regulatory subunit 8 Chain: A
Molecule details ›
Chain: A
Length: 78 amino acids
Theoretical weight: 8.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62195 (Residues: 318-395; Coverage: 19%)
Gene names: PSMC5, SUG1
Sequence domains: AAA+ lid domain
Structure domains: Helicase, Ruva Protein; domain 3

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P3121
Unit cell:
a: 82.415Å b: 82.415Å c: 26.001Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.227 0.253
Expression system: Escherichia coli

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