› 3kw3

X-ray diffraction
2.04Å resolution

Crystal structure of alanine racemase from Bartonella henselae with covalently bound pyridoxal phosphate

Released:
DOI: 10.2210/pdb3kw3/pdb
PDB entry 3kw3 coloured by chain, front view.
PDB entry 3kw3 coloured by chain, side view.
PDB entry 3kw3 coloured by chain, top view.
Source organism: Bartonella henselae
Primary publication:
SAD phasing using iodide ions in a high-throughput structural genomics environment.
Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE
J Struct Funct Genomics 12 83-95 (2011)
PMID: 21359836

Function and Biology Details

Reaction catalysed: 
L-alanine = D-alanine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102126 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alanine racemase Chains: A, B
Molecule details ›
Chains: A, B
Length: 376 amino acids
Theoretical weight: 41.56 KDa
Source organism: Bartonella henselae
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3LZE4 (Residues: 1-372; Coverage: 100%)
Gene names: BH12810, alr
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand LLP 2 x LLP

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3, RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 136.794Å b: 54.316Å c: 107.476Å
α: 90° β: 112.39° γ: 90°
R-values:
R R work R free
0.193 0.191 0.233
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes.
Lombardi et al. (2011)
3 more

5 mentions without citation

SAD phasing using iodide ions in a high-throughput structural genomics environment.
Abendroth et al. (2011)
4 more