X-ray diffraction
1.7Å resolution

Crystal structure of human protein syndesmos (NUDT16-like protein)

Source organism: Homo sapiens
Entry authors: Tresaugues L, Siponen MI, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Kallas A, Karlberg T, Kotenyova T, Kotzsch A, Kraulis P, Moche M, Nielsen TK, Nyman T, Persson C, Roos AK, Schuler H, Schutz P, Thorsell AG, Van Den Berg S, Weigelt J, Welin M, Wisniewska M, Nordlund P, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Tudor-interacting repair regulator protein Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 23.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9BRJ7 (Residues: 6-211; Coverage: 98%)
Gene names: NUDT16L1, SDOS, TIRR
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: C2
Unit cell:
a: 68.811Å b: 60.278Å c: 60.483Å
α: 90° β: 118.64° γ: 90°
R R work R free
0.185 0.184 0.217
Expression system: Escherichia coli