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Structure of KIAA1718 Jumonji domain

X-ray diffraction
2.29Å resolution
PDB entry 3kv9 coloured by chain, front view.
PDB entry 3kv9 coloured by chain, side view.
PDB entry 3kv9 coloured by chain, top view.
Source organism: Homo sapiens
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Lysine-specific demethylase 7A
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Multimeric state: monomeric
Accessible surface area: 16628.71 Å2
Buried surface area: 467.92 Å2
Dissociation area: 84.86 Å2
Dissociation energy (ΔGdiss): 10.29 kcal/mol
Dissociation entropy (TΔSdiss): -10.48 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-180579
Assembly 2
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Assembly Name: Lysine-specific demethylase 7A
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Multimeric state: homo dimer
Accessible surface area: 30831.44 Å2
Buried surface area: 3364.99 Å2
Dissociation area: 1,214.35 Å2
Dissociation energy (ΔGdiss): 0.64 kcal/mol
Dissociation entropy (TΔSdiss): 14.11 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-180580

Macromolecules

Lysine-specific demethylase 7A
Chain: A
Length: 397 amino acids
Theoretical weight: 46.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ZMT4 (Residues: 92-488; Coverage: 42%)
Gene names: JHDM1D, KDM7, KDM7A, KIAA1718
Pfam:
InterPro:
CATH:
Lysine-specific demethylase 7A in PDB entry 3kv9, assembly 1, front view.
Lysine-specific demethylase 7A in PDB entry 3kv9, assembly 1, side view.
Lysine-specific demethylase 7A in PDB entry 3kv9, assembly 1, top view.
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