Function and Biology

Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2

Source organism: Homo sapiens
Biochemical function: RNA binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF07145
Domain description: Ataxin-2 C-terminal region
Occurring in:
  1. Polyadenylate-binding protein-interacting protein 2
The deposited structure of PDB entry 3kut contains 2 copies of Pfam domain PF07145 (Ataxin-2 C-terminal region) in Polyadenylate-binding protein-interacting protein 2. Showing 1 copy in chain C.

PF00658
Domain description: Poly-adenylate binding protein, unique domain
Occurring in:
  1. Polyadenylate-binding protein 1
The deposited structure of PDB entry 3kut contains 2 copies of Pfam domain PF00658 (Poly-adenylate binding protein, unique domain) in Polyadenylate-binding protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002004
Domain description: Polyadenylate-binding protein/Hyperplastic disc protein
Occurring in:
  1. Polyadenylate-binding protein 1
IPR009818
Domain description: Ataxin-2, C-terminal
Occurring in:
  1. Polyadenylate-binding protein-interacting protein 2
IPR036053
Domain description: PABC (PABP) domain
Occurring in:
  1. Polyadenylate-binding protein 1

Structure domain

CATH CATH domain
1.10.1900.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: c-terminal domain of poly(a) binding protein
Homology: c-terminal domain of poly(a) binding protein
Occurring in:
  1. Polyadenylate-binding protein 1
The deposited structure of PDB entry 3kut contains 2 copies of CATH domain 1.10.1900.10 (c-terminal domain of poly(a) binding protein) in Polyadenylate-binding protein 1. Showing 1 copy in chain A.