PDBe 3kmu

X-ray diffraction
1.8Å resolution

Crystal structure of the ILK/alpha-parvin core complex (apo)

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin-linked protein kinase Chain: A
Molecule details ›
Chain: A
Length: 271 amino acids
Theoretical weight: 31.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13418 (Residues: 183-452; Coverage: 60%)
Gene names: ILK, ILK1, ILK2
Sequence domains: Protein tyrosine kinase
Structure domains:
Alpha-parvin Chain: B
Molecule details ›
Chain: B
Length: 129 amino acids
Theoretical weight: 14.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NVD7 (Residues: 248-372; Coverage: 34%)
Gene names: MXRA2, PARVA
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 44.38Å b: 117.715Å c: 47.344Å
α: 90° β: 101.68° γ: 90°
R-values:
R R work R free
0.202 0.2 0.236
Expression system: Escherichia coli