PDBe 3kg2

X-ray diffraction
3.6Å resolution

AMPA subtype ionotropic glutamate receptor in complex with competitive antagonist ZK 200775

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 823 amino acids
Theoretical weight: 92.04 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19491 (Residues: 25-847; Coverage: 95%)
  • Best match: P19491-2 (Residues: 25-847)
Gene names: Glur2, Gria2
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P1
Unit cell:
a: 90.715Å b: 109.848Å c: 161.13Å
α: 85.32° β: 84.75° γ: 78.92°
R-values:
R R work R free
0.287 0.286 0.296
Expression system: Escherichia coli