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Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine

Source organism: Homo sapiens
Biochemical function: nuclear receptor activity
Biological process: regulation of DNA-templated transcription
Cellular component: nucleus

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00104
Domain description: Ligand-binding domain of nuclear hormone receptor
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
The deposited structure of PDB entry 3kdu contains 2 copies of Pfam domain PF00104 (Ligand-binding domain of nuclear hormone receptor) in Peroxisome proliferator-activated receptor alpha. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR003074
Domain description: Peroxisome proliferator-activated receptor
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
IPR001723
Domain description: Nuclear hormone receptor
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
IPR000536
Domain description: Nuclear hormone receptor, ligand-binding domain
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
IPR003076
Domain description: Peroxisome proliferator-activated receptor alpha
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
IPR035500
Domain description: Nuclear hormone receptor-like domain superfamily
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha

Structure domain

CATH CATH domain
1.10.565.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Retinoid X Receptor
Homology: Retinoid X Receptor
Occurring in:
  1. Peroxisome proliferator-activated receptor alpha
The deposited structure of PDB entry 3kdu contains 2 copies of CATH domain 1.10.565.10 (Retinoid X Receptor) in Peroxisome proliferator-activated receptor alpha. Showing 1 copy in chain B.

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