3kdm

X-ray diffraction
1.5Å resolution

Crystal Structure of Human Anti-steroid Fab 5F2 in Complex with Testosterone

Released:
Source organism: Homo sapiens
Entry authors: Niemi MH, Rouvinen J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 218 amino acids
Theoretical weight: 23.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Immunoglobulin heavy chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 225 amino acids
Theoretical weight: 23.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P1
Unit cell:
a: 66.75Å b: 67.08Å c: 67.06Å
α: 81.32° β: 69.3° γ: 69.27°
R-values:
R R work R free
0.181 0.18 0.208
Expression system: Escherichia coli