Structure analysis

Transposase domain of Metnase

X-ray diffraction
2.55Å resolution
Source organism: Homo sapiens
Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1
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Multimeric state: homo dimer
Accessible surface area: 19800 Å2
Buried surface area: 2600 Å2
Dissociation area: 1,300 Å2
Dissociation energy (ΔGdiss): -5 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): 0 kcal/mol
Symmetry number: 2
Assembly 2 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly
Assembly 3
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: A, B
Length: 239 amino acids
Theoretical weight: 28.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q53H47 (Residues: 446-684; Coverage: 35%)
Gene name: SETMAR
Pfam: Transposase (partial DDE domain)
InterPro: Transposase, type 1
CATH: Ribonuclease H-like superfamily/Ribonuclease H

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