3k0w

X-ray diffraction
2.8Å resolution

Crystal structure of the tandem IG-like C2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1

Released:
Source organism: Homo sapiens
Entry authors: Walker JR, Qiu L, Butler-Cole C, Weigelt J, Bountra C, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 24.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UDY8 (Residues: 128-337; Coverage: 24%)
  • Best match: Q9UDY8-2 (Residues: 128-326)
Gene names: MALT1, MLT
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P6222
Unit cell:
a: 90.355Å b: 90.355Å c: 182.173Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.218 0.249
Expression system: Escherichia coli