Function and Biology

Heavy meromyosin from Schistosoma mansoni muscle thick filament by negative stain EM

Source organism: Schistosoma mansoni
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: myosin complex

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF02736
Domain description: Myosin N-terminal SH3-like domain
Occurring in:
  1. Myosin 2 heavy chain
1 copy of Pfam domain PF02736 (Myosin N-terminal SH3-like domain) in Myosin 2 heavy chain in PDB 3jax.

PF00063
Domain description: Myosin head (motor domain)
Occurring in:
  1. Myosin 2 heavy chain
1 copy of Pfam domain PF00063 (Myosin head (motor domain)) in Myosin 2 heavy chain in PDB 3jax.

PF13833
Domain description: EF-hand domain pair
Occurring in:
  1. Myosin regulatory light chain
1 copy of Pfam domain PF13833 (EF-hand domain pair) in Myosin regulatory light chain in PDB 3jax.

PF00612
Domain description: IQ calmodulin-binding motif
Occurring in:
  1. Myosin 2 heavy chain
1 copy of Pfam domain PF00612 (IQ calmodulin-binding motif) in Myosin 2 heavy chain in PDB 3jax.

PF13405
Domain description: EF-hand domain
Occurring in:
  1. Myosin regulatory light chain
1 copy of Pfam domain PF13405 (EF-hand domain) in Myosin regulatory light chain in PDB 3jax.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Smooth muscle myosin essential light chain
  2. Myosin regulatory light chain
IPR001609
Domain description: Myosin head, motor domain
Occurring in:
  1. Myosin 2 heavy chain
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Smooth muscle myosin essential light chain
  2. Myosin regulatory light chain
IPR000048
Domain description: IQ motif, EF-hand binding site
Occurring in:
  1. Myosin 2 heavy chain
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Myosin 2 heavy chain
IPR008989
Domain description: Myosin S1 fragment, N-terminal
Occurring in:
  1. Myosin 2 heavy chain
IPR027401
Domain description: Myosin IQ motif-containing domain superfamily
Occurring in:
  1. Myosin 2 heavy chain
IPR036961
Domain description: Kinesin motor domain superfamily
Occurring in:
  1. Myosin 2 heavy chain
IPR004009
Domain description: Myosin, N-terminal, SH3-like
Occurring in:
  1. Myosin 2 heavy chain