› 3jax

Electron Microscopy
23Å resolution

Heavy meromyosin from Schistosoma mansoni muscle thick filament by negative stain EM

Released:
DOI: 10.2210/pdb3jax/pdb
PDB 3jax coloured by chain and viewed from the front.
PDB 3jax coloured by chain and viewed from the side.
PDB 3jax coloured by chain and viewed from the top.
Source organism: Schistosoma mansoni
Primary publication:
An invertebrate smooth muscle with striated muscle myosin filaments.
Sulbar��n G, Alamo L, Pinto A, M��rquez G, M��ndez F, Padr��n R, Craig R
Proc. Natl. Acad. Sci. U.S.A. (2015)
PMID: 26443857
Related structures: EMD-6370

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero 120-mer (preferred)
hetero hexamer
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myosin 2 heavy chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 974 amino acids
Theoretical weight: 112.18 KDa
Source organism: Schistosoma mansoni
UniProt:
  • Canonical: A0A0R4I956 (Residues: 1-974; Coverage: 100%)
Sequence domains: Myosin head (motor domain)
Smooth muscle myosin essential light chain Chains: C, D
Molecule details ›
Chains: C, D
Length: 151 amino acids
Theoretical weight: 17 KDa
Source organism: Schistosoma mansoni
UniProt:
  • Canonical: A0A0R4I957 (Residues: 1-151; Coverage: 100%)
Myosin regulatory light chain Chains: E, F
Molecule details ›
Chains: E, F
Length: 196 amino acids
Theoretical weight: 21.71 KDa
Source organism: Schistosoma mansoni
UniProt:
  • Canonical: A0A0R4I958 (Residues: 1-196; Coverage: 100%)
Sequence domains: EF-hand domain pair

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 23Å
Relevant EMDB volumes: EMD-6370

Quick links

Citations

3 review citations

Structural basis of the super- and hyper-relaxed states of myosin II.
Craig et al. (2022)
2 more