› 3j9m

Electron Microscopy
3.5Å resolution

Structure of the human mitochondrial ribosome (class 1)

Released:
DOI: 10.2210/pdb3j9m/pdb
PDB 3j9m coloured by chain and viewed from the front.
PDB 3j9m coloured by chain and viewed from the side.
PDB 3j9m coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Ribosome. The structure of the human mitochondrial ribosome.
Amunts A, Brown A, Toots J, Scheres SH, Ramakrishnan V
Science 348 95-8 (2015)
PMID: 25838379
Related structures: EMD-2876

Function and Biology Details

Reaction catalysed: 
N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 85-mer (preferred)
Entry contents:
81 distinct polypeptide molecules
4 distinct RNA molecules
Macromolecules (85 distinct):
39S ribosomal protein L2, mitochondrial Chain: D
Molecule details ›
Chain: D
Length: 305 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q5T653 (Residues: 1-305; Coverage: 100%)
Gene names: CGI-22, MRPL2
Sequence domains: Ribosomal Proteins L2, C-terminal domain
39S ribosomal protein L3, mitochondrial Chain: E
Molecule details ›
Chain: E
Length: 348 amino acids
Theoretical weight: 38.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P09001 (Residues: 1-348; Coverage: 100%)
Gene names: MRL3, MRPL3, RPML3
39S ribosomal protein L4, mitochondrial Chain: F
Molecule details ›
Chain: F
Length: 311 amino acids
Theoretical weight: 34.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD3 (Residues: 1-311; Coverage: 100%)
Gene names: CDABP0091, CGI-28, MRPL4
Sequence domains: Ribosomal protein L4/L1 family
39S ribosomal protein L9, mitochondrial Chain: H
Molecule details ›
Chain: H
Length: 267 amino acids
Theoretical weight: 30.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD2 (Residues: 1-267; Coverage: 100%)
Gene name: MRPL9
Sequence domains: Ribosomal protein L9, N-terminal domain
39S ribosomal protein L10, mitochondrial Chain: I
Molecule details ›
Chain: I
Length: 261 amino acids
Theoretical weight: 29.32 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z7H8 (Residues: 1-261; Coverage: 100%)
Gene names: MRPL10, MRPL8, RPML8
39S ribosomal protein L11, mitochondrial Chain: J
Molecule details ›
Chain: J
Length: 192 amino acids
Theoretical weight: 20.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3B7 (Residues: 1-192; Coverage: 100%)
Gene names: CGI-113, MRPL11
39S ribosomal protein L13, mitochondrial Chain: K
Molecule details ›
Chain: K
Length: 178 amino acids
Theoretical weight: 20.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD1 (Residues: 1-178; Coverage: 100%)
Gene name: MRPL13
39S ribosomal protein L14, mitochondrial Chain: L
Molecule details ›
Chain: L
Length: 145 amino acids
Theoretical weight: 15.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6P1L8 (Residues: 1-145; Coverage: 100%)
Gene names: MRPL14, MRPL32, RPML32
Sequence domains: Ribosomal protein L14p/L23e
39S ribosomal protein L15, mitochondrial Chain: M
Molecule details ›
Chain: M
Length: 296 amino acids
Theoretical weight: 33.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P015 (Residues: 1-296; Coverage: 100%)
Gene names: HSPC145, MRPL15
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
39S ribosomal protein L16, mitochondrial Chain: N
Molecule details ›
Chain: N
Length: 251 amino acids
Theoretical weight: 28.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NX20 (Residues: 1-251; Coverage: 100%)
Gene names: MRPL16, PNAS-111
Sequence domains: Ribosomal protein L16p/L10e
39S ribosomal protein L17, mitochondrial Chain: O
Molecule details ›
Chain: O
Length: 175 amino acids
Theoretical weight: 20.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NRX2 (Residues: 1-175; Coverage: 100%)
Gene names: LIP2, MRPL17
Sequence domains: Ribosomal protein L17
Mitochondrial ribosomal protein L18, isoform CRA_b Chain: P
Molecule details ›
Chain: P
Length: 179 amino acids
Theoretical weight: 20.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A8K9D2 (Residues: 1-179; Coverage: 100%)
Gene names: MRPL18, hCG_34030
Sequence domains: Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
39S ribosomal protein L19, mitochondrial Chain: Q
Molecule details ›
Chain: Q
Length: 292 amino acids
Theoretical weight: 33.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49406 (Residues: 1-292; Coverage: 100%)
Gene names: KIAA0104, MRPL15, MRPL19
Sequence domains: Ribosomal protein L19
39S ribosomal protein L20, mitochondrial Chain: R
Molecule details ›
Chain: R
Length: 149 amino acids
Theoretical weight: 17.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYC9 (Residues: 1-149; Coverage: 100%)
Gene name: MRPL20
Sequence domains: Ribosomal protein L20
39S ribosomal protein L21, mitochondrial Chain: S
Molecule details ›
Chain: S
Length: 205 amino acids
Theoretical weight: 22.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z2W9 (Residues: 1-205; Coverage: 100%)
Gene name: MRPL21
Sequence domains: Ribosomal prokaryotic L21 protein
39S ribosomal protein L22, mitochondrial Chain: T
Molecule details ›
Chain: T
Length: 212 amino acids
Theoretical weight: 24.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: E7ESL0 (Residues: 1-212; Coverage: 100%)
Gene name: MRPL22
39S ribosomal protein L23, mitochondrial Chain: U
Molecule details ›
Chain: U
Length: 153 amino acids
Theoretical weight: 17.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16540 (Residues: 1-153; Coverage: 100%)
Gene names: L23MRP, MRPL23, RPL23L
39S ribosomal protein L24, mitochondrial Chain: V
Molecule details ›
Chain: V
Length: 216 amino acids
Theoretical weight: 24.95 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96A35 (Residues: 1-216; Coverage: 100%)
Gene name: MRPL24
Sequence domains: KOW motif
39S ribosomal protein L27, mitochondrial Chain: W
Molecule details ›
Chain: W
Length: 148 amino acids
Theoretical weight: 16.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P0M9 (Residues: 1-148; Coverage: 100%)
Gene names: HSPC250, MRPL27
Sequence domains: Ribosomal L27 protein
bL28m Chain: X
Molecule details ›
Chain: X
Length: 256 amino acids
Theoretical weight: 30.09 KDa
Source organism: Homo sapiens
39S ribosomal protein L47, mitochondrial Chain: Y
Molecule details ›
Chain: Y
Length: 250 amino acids
Theoretical weight: 29.51 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9HD33 (Residues: 1-250; Coverage: 100%)
Gene names: CGI-204, MRPL47, NCM1
39S ribosomal protein L30, mitochondrial Chain: Z
Molecule details ›
Chain: Z
Length: 161 amino acids
Theoretical weight: 18.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8TCC3 (Residues: 1-161; Coverage: 100%)
Gene names: HSPC249, MRPL28, MRPL30, RPML28
39S ribosomal protein L32, mitochondrial Chain: 0
Molecule details ›
Chain: 0
Length: 188 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYC8 (Residues: 1-188; Coverage: 100%)
Gene names: HSPC283, MRPL32
Sequence domains: Ribosomal L32p protein family
39S ribosomal protein L33, mitochondrial Chain: 1
Molecule details ›
Chain: 1
Length: 65 amino acids
Theoretical weight: 7.64 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75394 (Residues: 1-65; Coverage: 100%)
Gene names: C2orf1, MRPL33
Sequence domains: Ribosomal protein L33
39S ribosomal protein L34, mitochondrial Chain: 2
Molecule details ›
Chain: 2
Length: 92 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BQ48 (Residues: 1-92; Coverage: 100%)
Gene name: MRPL34
39S ribosomal protein L35, mitochondrial Chain: 3
Molecule details ›
Chain: 3
Length: 188 amino acids
Theoretical weight: 21.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NZE8 (Residues: 1-188; Coverage: 100%)
Gene names: BM-007, MRPL35
39S ribosomal protein L36, mitochondrial Chain: 4
Molecule details ›
Chain: 4
Length: 103 amino acids
Theoretical weight: 11.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P0J6 (Residues: 1-103; Coverage: 100%)
Gene names: BRIP1, MRPL36
39S ribosomal protein L37, mitochondrial Chain: 5
Molecule details ›
Chain: 5
Length: 423 amino acids
Theoretical weight: 48.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BZE1 (Residues: 1-423; Coverage: 100%)
Gene names: HSPC235, MRPL2, MRPL37, RPML2
Sequence domains: Mitochondrial 28S ribosomal protein S30 (PDCD9)
39S ribosomal protein L38, mitochondrial Chain: 6
Molecule details ›
Chain: 6
Length: 380 amino acids
Theoretical weight: 44.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96DV4 (Residues: 1-380; Coverage: 100%)
Gene names: HSPC262, MRPL38
39S ribosomal protein L39, mitochondrial Chain: 7
Molecule details ›
Chain: 7
Length: 338 amino acids
Theoretical weight: 38.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NYK5 (Residues: 1-338; Coverage: 100%)
Gene names: C21orf92, MRPL39, MRPL5, MSTP003, PRED22, RPML5
39S ribosomal protein L40, mitochondrial Chain: 8
Molecule details ›
Chain: 8
Length: 206 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NQ50 (Residues: 1-206; Coverage: 100%)
Gene names: MRPL40, NLVCF, URIM
Sequence domains: Mitochondrial ribosomal protein L28
39S ribosomal protein L41, mitochondrial Chain: 9
Molecule details ›
Chain: 9
Length: 137 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8IXM3 (Residues: 1-137; Coverage: 100%)
Gene names: BMRP, MRPL27, MRPL41, PIG3, RPML27
Sequence domains: Mitochondrial ribosomal protein L27
39S ribosomal protein L42, mitochondrial Chain: a
Molecule details ›
Chain: a
Length: 142 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y6G3 (Residues: 1-142; Coverage: 100%)
Gene names: HSPC204, MRPL31, MRPL42, MRPS32, PTD007, RPML31
Sequence domains: Mitochondrial 28S ribosomal protein S32
39S ribosomal protein L43, mitochondrial Chain: b
Molecule details ›
Chain: b
Length: 155 amino acids
Theoretical weight: 17.45 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8N983 (Residues: 1-155; Coverage: 72%)
Gene name: MRPL43
39S ribosomal protein L44, mitochondrial Chain: c
Molecule details ›
Chain: c
Length: 332 amino acids
Theoretical weight: 37.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9H9J2 (Residues: 1-332; Coverage: 100%)
Gene name: MRPL44
39S ribosomal protein L45, mitochondrial Chain: d
Molecule details ›
Chain: d
Length: 306 amino acids
Theoretical weight: 35.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BRJ2 (Residues: 1-306; Coverage: 100%)
Gene name: MRPL45
Sequence domains: Tim44-like domain
39S ribosomal protein L46, mitochondrial Chain: e
Molecule details ›
Chain: e
Length: 279 amino acids
Theoretical weight: 31.75 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9H2W6 (Residues: 1-279; Coverage: 100%)
Gene names: C15orf4, LIECG2, MRPL46
39S ribosomal protein L48, mitochondrial Chain: f
Molecule details ›
Chain: f
Length: 194 amino acids
Theoretical weight: 21.86 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96GC5 (Residues: 1-194; Coverage: 92%)
Gene names: CGI-118, HSPC290, MRPL48
Sequence domains: Ribosomal protein S10p/S20e
39S ribosomal protein L49, mitochondrial Chain: g
Molecule details ›
Chain: g
Length: 166 amino acids
Theoretical weight: 19.23 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13405 (Residues: 1-166; Coverage: 100%)
Gene names: C11orf4, MRPL49, NOF1, OK/SW-cl.67
Sequence domains: Mitochondrial large subunit ribosomal protein (Img2)
39S ribosomal protein L50, mitochondrial Chain: h
Molecule details ›
Chain: h
Length: 158 amino acids
Theoretical weight: 18.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8N5N7 (Residues: 1-158; Coverage: 100%)
Gene name: MRPL50
39S ribosomal protein L51, mitochondrial Chain: i
Molecule details ›
Chain: i
Length: 128 amino acids
Theoretical weight: 15.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q4U2R6 (Residues: 1-128; Coverage: 100%)
Gene names: CDA09, HSPC241, MRP64, MRPL51
Sequence domains: Mitochondrial ribosomal subunit
39S ribosomal protein L52, mitochondrial Chain: j
Molecule details ›
Chain: j
Length: 123 amino acids
Theoretical weight: 13.7 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A8K7J6 (Residues: 1-123; Coverage: 100%)
Sequence domains: Mitoribosomal protein mL52
39S ribosomal protein L53, mitochondrial Chain: k
Molecule details ›
Chain: k
Length: 112 amino acids
Theoretical weight: 12.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EL3 (Residues: 1-112; Coverage: 100%)
Gene name: MRPL53
Sequence domains: 39S ribosomal protein L53/MRP-L53
39S ribosomal protein L54, mitochondrial Chain: l
Molecule details ›
Chain: l
Length: 138 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6P161 (Residues: 1-138; Coverage: 100%)
Gene name: MRPL54
Sequence domains: Mitochondrial ribosomal protein L37
39S ribosomal protein L55, mitochondrial Chain: m
Molecule details ›
Chain: m
Length: 128 amino acids
Theoretical weight: 15.16 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z7F7 (Residues: 1-128; Coverage: 100%)
Gene names: MRPL55, UNQ5835/PRO19675
Sequence domains: Mitochondrial ribosomal protein L55
Ribosomal protein 63, mitochondrial Chain: o
Molecule details ›
Chain: o
Length: 102 amino acids
Theoretical weight: 12.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BQC6 (Residues: 1-102; Coverage: 100%)
Gene names: MRP63, MRPL57
Sequence domains: Mitochondrial ribosome protein 63
Peptidyl-tRNA hydrolase ICT1, mitochondrial Chain: p
Molecule details ›
Chain: p
Length: 206 amino acids
Theoretical weight: 23.67 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14197 (Residues: 1-206; Coverage: 100%)
Gene names: DS1, ICT1, MRPL58
Growth arrest and DNA damage-inducible proteins-interacting protein 1 Chain: q
Molecule details ›
Chain: q
Length: 222 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8TAE8 (Residues: 1-222; Coverage: 100%)
Gene names: GADD45GIP1, MRPL59, PLINP1, PRG6
Sequence domains: Growth arrest and DNA-damage-inducible proteins-interacting protein 1
39S ribosomal protein S18a, mitochondrial Chain: r
Molecule details ›
Chain: r
Length: 196 amino acids
Theoretical weight: 22.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NVS2 (Residues: 1-196; Coverage: 100%)
Gene name: MRPS18A
Sequence domains: Ribosomal protein S18
39S ribosomal protein S30, mitochondrial Chain: s
Molecule details ›
Chain: s
Length: 439 amino acids
Theoretical weight: 50.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NP92 (Residues: 1-439; Coverage: 100%)
Gene names: BM-047, MRPS30, PDCD9
Sequence domains: Mitochondrial 28S ribosomal protein S30 (PDCD9)
Unknown protein/protein extension Chain: t
Molecule details ›
Chain: t
Length: 28 amino acids
Theoretical weight: 2.4 KDa
Source organism: Homo sapiens
28S ribosomal protein S2, mitochondrial Chain: AB
Molecule details ›
Chain: AB
Length: 296 amino acids
Theoretical weight: 33.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y399 (Residues: 1-296; Coverage: 100%)
Gene names: CGI-91, MRPS2
28S ribosomal protein S24, mitochondrial Chain: AC
Molecule details ›
Chain: AC
Length: 167 amino acids
Theoretical weight: 19.05 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EL2 (Residues: 1-167; Coverage: 100%)
Gene names: HSPC335, MRPS24
Sequence domains: Mitochondrial ribosome subunit S24
28S ribosomal protein S5, mitochondrial Chain: AD
Molecule details ›
Chain: AD
Length: 430 amino acids
Theoretical weight: 48.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82675 (Residues: 1-430; Coverage: 100%)
Gene name: MRPS5
Sequence domains:
28S ribosomal protein S6, mitochondrial Chain: AE
Molecule details ›
Chain: AE
Length: 125 amino acids
Theoretical weight: 14.25 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82932 (Residues: 1-125; Coverage: 100%)
Gene names: C21orf101, MRPS6, RPMS6
Sequence domains: Ribosomal protein S6
28S ribosomal protein S7, mitochondrial Chain: AF
Molecule details ›
Chain: AF
Length: 242 amino acids
Theoretical weight: 28.19 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2R9 (Residues: 1-242; Coverage: 100%)
Gene name: MRPS7
28S ribosomal protein S9, mitochondrial Chain: AG
Molecule details ›
Chain: AG
Length: 396 amino acids
Theoretical weight: 45.91 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82933 (Residues: 1-396; Coverage: 100%)
Gene names: MRPS9, RPMS9
Sequence domains: Ribosomal protein S9/S16
28S ribosomal protein S10, mitochondrial Chain: AH
Molecule details ›
Chain: AH
Length: 201 amino acids
Theoretical weight: 23.03 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82664 (Residues: 1-201; Coverage: 100%)
Gene names: MRPS10, MSTP040
Sequence domains: Ribosomal protein S10p/S20e
28S ribosomal protein S11, mitochondrial Chain: AI
Molecule details ›
Chain: AI
Length: 194 amino acids
Theoretical weight: 20.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82912 (Residues: 1-194; Coverage: 100%)
Gene names: HCC2, MRPS11, RPMS11
Sequence domains: Ribosomal protein S11
28S ribosomal protein S12, mitochondrial Chain: AJ
Molecule details ›
Chain: AJ
Length: 138 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O15235 (Residues: 1-138; Coverage: 100%)
Gene names: MRPS12, RPMS12, RPSM12
28S ribosomal protein S14, mitochondrial Chain: AK
Molecule details ›
Chain: AK
Length: 128 amino acids
Theoretical weight: 15.17 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O60783 (Residues: 1-128; Coverage: 100%)
Gene name: MRPS14
Sequence domains: Ribosomal protein S14p/S29e
28S ribosomal protein S15, mitochondrial Chain: AL
Molecule details ›
Chain: AL
Length: 257 amino acids
Theoretical weight: 29.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82914 (Residues: 1-257; Coverage: 100%)
Gene names: DC37, MRPS15, RPMS15
Sequence domains: Ribosomal protein S15
28S ribosomal protein S16, mitochondrial Chain: AM
Molecule details ›
Chain: AM
Length: 137 amino acids
Theoretical weight: 15.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D3 (Residues: 1-137; Coverage: 100%)
Gene names: CGI-132, MRPS16, RPMS16
Sequence domains: Ribosomal protein S16
28S ribosomal protein S17, mitochondrial Chain: AN
Molecule details ›
Chain: AN
Length: 130 amino acids
Theoretical weight: 14.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2R5 (Residues: 1-130; Coverage: 100%)
Gene names: HSPC011, MRPS17, RPMS17
Sequence domains: Ribosomal protein S17
28S ribosomal protein S18b, mitochondrial Chain: AO
Molecule details ›
Chain: AO
Length: 258 amino acids
Theoretical weight: 29.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y676 (Residues: 1-258; Coverage: 100%)
Gene names: C6orf14, HSPC183, MRPS18B, PTD017
Sequence domains: Ribosomal protein S18
28S ribosomal protein S18c, mitochondrial Chain: AP
Molecule details ›
Chain: AP
Length: 142 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D5 (Residues: 1-142; Coverage: 100%)
Gene names: CGI-134, MRPS18C
28S ribosomal protein S21, mitochondrial Chain: AQ
Molecule details ›
Chain: AQ
Length: 87 amino acids
Theoretical weight: 10.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82921 (Residues: 1-87; Coverage: 100%)
Gene names: MDS016, MRPS21, RPMS21
28S ribosomal protein S22, mitochondrial Chain: AR
Molecule details ›
Chain: AR
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82650 (Residues: 1-360; Coverage: 100%)
Gene names: C3orf5, GK002, MRPS22, RPMS22
28S ribosomal protein S23, mitochondrial Chain: AS
Molecule details ›
Chain: AS
Length: 190 amino acids
Theoretical weight: 21.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D9 (Residues: 1-190; Coverage: 100%)
Gene names: CGI-138, HSPC329, MRPS23
28S ribosomal protein S25, mitochondrial Chain: AT
Molecule details ›
Chain: AT
Length: 173 amino acids
Theoretical weight: 20.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82663 (Residues: 1-173; Coverage: 100%)
Gene names: MRPS25, RPMS25
28S ribosomal protein S26, mitochondrial Chain: AU
Molecule details ›
Chain: AU
Length: 205 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYN8 (Residues: 1-205; Coverage: 100%)
Gene names: C20orf193, MRPS26, RPMS13
Sequence domains: Mitochondrial ribosome subunit S26
28S ribosomal protein S27, mitochondrial Chain: AV
Molecule details ›
Chain: AV
Length: 414 amino acids
Theoretical weight: 47.67 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q92552 (Residues: 1-414; Coverage: 100%)
Gene names: KIAA0264, MRPS27
28S ribosomal protein S28, mitochondrial Chain: AW
Molecule details ›
Chain: AW
Length: 187 amino acids
Theoretical weight: 20.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2Q9 (Residues: 1-187; Coverage: 100%)
Gene names: HSPC007, MRPS28, MRPS35
Sequence domains: Mitochondrial ribosomal protein MRP-S35
28S ribosomal protein S29, mitochondrial Chain: AX
Molecule details ›
Chain: AX
Length: 398 amino acids
Theoretical weight: 45.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P51398 (Residues: 1-398; Coverage: 100%)
Gene names: DAP3, MRPS29
Sequence domains: Mitochondrial ribosomal death-associated protein 3
28S ribosomal protein S31, mitochondrial Chain: AY
Molecule details ›
Chain: AY
Length: 395 amino acids
Theoretical weight: 45.39 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q92665 (Residues: 1-395; Coverage: 100%)
Gene names: IMOGN38, MRPS31
Sequence domains: Mitochondrial 28S ribosomal protein S31
28S ribosomal protein S33, mitochondrial Chain: AZ
Molecule details ›
Chain: AZ
Length: 106 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y291 (Residues: 1-106; Coverage: 100%)
Gene names: CGI-139, MRPS33, PTD003
28S ribosomal protein S34, mitochondrial Chain: A0
Molecule details ›
Chain: A0
Length: 218 amino acids
Theoretical weight: 25.7 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82930 (Residues: 1-218; Coverage: 100%)
Gene name: MRPS34
Sequence domains: Mitochondrial 28S ribosomal protein S34
28S ribosomal protein S35, mitochondrial Chain: A1
Molecule details ›
Chain: A1
Length: 323 amino acids
Theoretical weight: 36.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82673 (Residues: 1-323; Coverage: 100%)
Gene names: HDCMD11P, MDS023, MRPS28, MRPS35, PSEC0213
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 Chain: A2
Molecule details ›
Chain: A2
Length: 118 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96BP2 (Residues: 1-118; Coverage: 100%)
Gene names: C10orf34, CHCHD1, MRPS37
Aurora kinase A-interacting protein Chain: A3
Molecule details ›
Chain: A3
Length: 199 amino acids
Theoretical weight: 22.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NWT8 (Residues: 1-199; Coverage: 100%)
Gene names: AIP, AKIP, AURKAIP1, MRPS38
Pentatricopeptide repeat domain-containing protein 3, mitochondrial Chain: A4
Molecule details ›
Chain: A4
Length: 579 amino acids
Theoretical weight: 61.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EY7 (Residues: 1-689; Coverage: 84%)
  • Best match: Q96EY7-2 (Residues: 5-280)
Gene names: MRPS39, PTCD3, TRG15
Sequence domains: Pentatricopeptide repeat domain
16S ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 1559 nucleotides
Theoretical weight: 500.02 KDa
Sequence domains: Bacterial large subunit ribosomal RNA
mt-tRNAVal Chain: B
Molecule details ›
Chain: B
Length: 73 nucleotides
Theoretical weight: 23.27 KDa
E-site tRNA Chain: u
Molecule details ›
Chain: u
Length: 2 nucleotides
Theoretical weight: 589 Da
12S rRNA Chain: AA
Molecule details ›
Chain: AA
Length: 954 nucleotides
Theoretical weight: 306.11 KDa
Sequence domains: Bacterial small subunit ribosomal RNA

Ligands and Environments

3 bound ligands:
Ligand MG 127 x MG
Ligand ZN 7 x ZN
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-2876

Quick links

Citations

51 review citations

Mechanisms and regulation of protein synthesis in mitochondria.
Kummer et al. (2021)
50 more

7 mentions without citation

Revising the Structural Diversity of Ribosomal Proteins Across the Three Domains of Life.
Melnikov et al. (2018)
6 more