Electron Microscopy
7.7Å resolution

Electron cryo-microscopy of DNGR-1 in complex with F-actin


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
C-type lectin domain family 9 member A Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.97 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
  • Canonical: Q8BRU4 (Residues: 108-238; Coverage: 55%)
Gene names: Clec9a, Dngr-1
Sequence domains: Lectin C-type domain
Actin, cytoplasmic 1 Chains: B, C, D
Molecule details ›
Chains: B, C, D
Length: 374 amino acids
Theoretical weight: 41.66 KDa
Source organism: Homo sapiens
  • Canonical: P60709 (Residues: 2-375; Coverage: 100%)
Gene name: ACTB
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Resolution: 7.7Å
Relevant EMDB volumes: EMD-6102
Expression system: Homo sapiens