Structure analysis

Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron microscopy

Electron Microscopy
35Å resolution
Source organisms:
Assembly composition:
hetero pentamer (preferred)
Entry contents: 3 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero pentamer

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 353 amino acids
Theoretical weight: 39.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q6JP77 (Residues: 1-353; Coverage: 100%)
Gene names: Akap18, Akap7
Pfam:
InterPro:

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Chains: B, C
Length: 402 amino acids
Theoretical weight: 45.64 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12367 (Residues: 1-21, 22-401; Coverage: 100%)
Gene name: Prkar2a
Pfam:
InterPro:

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Chains: D, E
Length: 351 amino acids
Theoretical weight: 40.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05132 (Residues: 1-351; Coverage: 100%)
Gene names: Pkaca, Prkaca
Pfam: Protein kinase domain
InterPro:

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