Electron Microscopy
25Å resolution

Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy

Source organisms:
Related structures: EMD-5679

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Lens fiber major intrinsic protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 263 amino acids
Theoretical weight: 28.24 KDa
Source organism: Ovis aries
  • Canonical: Q6J8I9 (Residues: 1-263; Coverage: 100%)
Gene names: AQP0, MIP
Sequence domains: Major intrinsic protein
Calmodulin-1 Chains: E, F
Molecule details ›
Chains: E, F
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 25Å
Relevant EMDB volumes: EMD-5679
Expression system: Escherichia coli BL21