X-ray diffraction
1.4Å resolution

LasR-OC12 HSL complex

Source organism: Pseudomonas aeruginosa
Entry authors: Zou Y, Nair SK

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Transcriptional activator protein LasR Chains: A, B
Molecule details ›
Chains: A, B
Length: 173 amino acids
Theoretical weight: 19.32 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
  • Canonical: P25084 (Residues: 1-173; Coverage: 72%)
Gene names: PA1430, lasR
Sequence domains: Autoinducer binding domain
Structure domains: Transcription factor LuxR-like, autoinducer-binding domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 54.293Å b: 67.616Å c: 54.396Å
α: 90° β: 115.04° γ: 90°
R R work R free
0.17 0.168 0.207
Expression system: Escherichia coli