› 3ix3

X-ray diffraction
1.4Å resolution

LasR-OC12 HSL complex

Released:
DOI: 10.2210/pdb3ix3/pdb
PDB 3ix3 coloured by chain and viewed from the front.
PDB 3ix3 coloured by chain and viewed from the side.
PDB 3ix3 coloured by chain and viewed from the top.
Source organism: Pseudomonas aeruginosa
Entry authors: Zou Y, Nair SK

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional activator protein LasR Chains: A, B
Molecule details ›
Chains: A, B
Length: 173 amino acids
Theoretical weight: 19.32 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: P25084 (Residues: 1-173; Coverage: 72%)
Gene names: PA1430, lasR
Sequence domains: Autoinducer binding domain
Structure domains: Transcription factor LuxR-like, autoinducer-binding domain

Ligands and Environments

1 bound ligand:
Ligand OHN 2 x OHN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 54.293Å b: 67.616Å c: 54.396Å
α: 90° β: 115.04° γ: 90°
R-values:
R R work R free
0.17 0.168 0.207
Expression system: Escherichia coli

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