X-ray diffraction
3.63Å resolution

Huntingtin amino-terminal region with 17 Gln residues - Crystal C90


Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Huntingtin; Maltose/maltodextrin-binding periplasmic protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 449 amino acids
Theoretical weight: 49.32 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P0AEY0 (Residues: 27-384; Coverage: 97%)
  • Canonical: P42858 (Residues: 1-64; Coverage: 2%)
Gene names: ECs5017, HD, HTT, IT15, Z5632, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 162.95Å b: 101.21Å c: 142.05Å
α: 90° β: 90.42° γ: 90°
R R work R free
0.254 0.251 0.304
Expression system: Escherichia coli