PDBe 3inb

X-ray diffraction
3.1Å resolution

Structure of the measles virus hemagglutinin bound to the CD46 receptor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin glycoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 466 amino acids
Theoretical weight: 51.56 KDa
Source organism: Measles virus strain Edmonston
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P08362 (Residues: 179-617; Coverage: 71%)
Gene name: H
Structure domains: Neuraminidase
Membrane cofactor protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 126 amino acids
Theoretical weight: 14.52 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P15529 (Residues: 35-160; Coverage: 35%)
Gene names: CD46, MCP, MIC10
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P2221
Unit cell:
a: 81.365Å b: 105.833Å c: 208.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.227 0.259
Expression system: Cricetulus griseus