X-ray diffraction
1.64Å resolution

Crystal structure of mouse Bcl-xl mutant (Y101A) at pH 6.0

Source organism: Mus musculus
Primary publication:
Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol.
Biochem. Biophys. Res. Commun. 394 515-21 (2010)
PMID: 20206602

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 22.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: Q64373 (Residues: 1-196; Coverage: 84%)
Gene names: Bcl2l, Bcl2l1, Bclx
Sequence domains:
Structure domains: Blc2-like

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P41212
Unit cell:
a: 62.86Å b: 62.86Å c: 110.267Å
α: 90° β: 90° γ: 90°
R R work R free
0.208 0.206 0.244
Expression system: Escherichia coli