X-ray diffraction
2.2Å resolution

A 2.2A crystal structure of the AP2 domain of PF14_0633 from P. falciparum, bound as a domain-swapped dimer to its cognate DNA

Source organism: Plasmodium falciparum 3D7
Entry authors: Lindner SE, De Silva E, Keck JL, Llinas M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
AP2/ERF domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 77 amino acids
Theoretical weight: 8.82 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
  • Canonical: Q8IKH2 (Residues: 63-123; Coverage: 8%)
Gene name: PF3D7_1466400
Sequence domains: AP2 domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
5'-D(*TP*GP*CP*AP*TP*GP*CP*A)-3' Chains: C, D, W, X
Molecule details ›
Chains: C, D, W, X
Length: 8 nucleotides
Theoretical weight: 2.43 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: C2221
Unit cell:
a: 43.81Å b: 58.821Å c: 177.296Å
α: 90° β: 90° γ: 90°
R R work R free
0.217 0.214 0.263
Expression systems:
  • Escherichia coli
  • Not provided