PDBe 3ifo

X-ray diffraction
2.15Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
10D5 FAB antibody heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 226 amino acids
Theoretical weight: 24.26 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
10D5 FAB antibody light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 219 amino acids
Theoretical weight: 24.22 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
Amyloid-beta protein 40 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 7 amino acids
Theoretical weight: 891 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 672-678; Coverage: 1%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P212121
Unit cell:
a: 96.31Å b: 99.97Å c: 103.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.162 0.218
Expression systems:
  • Mus musculus
  • Not provided