3i7o

X-ray diffraction
2.8Å resolution

Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA damage-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 1143 amino acids
Theoretical weight: 127.4 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q16531 (Residues: 1-1140; Coverage: 100%)
Gene names: DDB1, XAP1
Sequence domains:
Structure domains:
DDB1- and CUL4-associated factor 6 Chain: B
Molecule details ›
Chain: B
Length: 13 amino acids
Theoretical weight: 1.6 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q58WW2 (Residues: 9-21; Coverage: 2%)
Gene names: DCAF6, IQWD1, MSTP055

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 63.759Å b: 131.94Å c: 181.271Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.28 0.256 0.32
Expression systems:
  • Spodoptera frugiperda
  • Not provided