X-ray diffraction
3.46Å resolution

Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3)

Source organism: Danio rerio

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
P2X purinoceptor Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 356 amino acids
Theoretical weight: 40.19 KDa
Source organism: Danio rerio
Expression system: Spodoptera frugiperda
  • Canonical: Q6NYR1 (Residues: 28-381; Coverage: 91%)
Gene name: p2rx4a
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: R3
Unit cell:
a: 234.91Å b: 234.91Å c: 138.433Å
α: 90° β: 90° γ: 120°
R R work R free
0.277 0.276 0.289
Expression system: Spodoptera frugiperda