PDBe 3i4r

X-ray diffraction
3.53Å resolution

Nup107(aa658-925)/Nup133(aa517-1156) complex, H.sapiens

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear pore complex protein Nup107 Chain: A
Molecule details ›
Chain: A
Length: 277 amino acids
Theoretical weight: 32.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P57740 (Residues: 658-925; Coverage: 29%)
  • Best match: P57740-3 (Residues: 427-686)
Gene name: NUP107
Structure domains: Delta-Endotoxin; domain 1
Nuclear pore complex protein Nup133 Chain: B
Molecule details ›
Chain: B
Length: 644 amino acids
Theoretical weight: 74.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WUM0 (Residues: 517-1156; Coverage: 55%)
Gene name: NUP133
Sequence domains: Non-repetitive/WGA-negative nucleoporin C-terminal
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 115.554Å b: 133.047Å c: 176.303Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.32 0.315 0.37
Expression system: Escherichia coli