› 3i36

X-ray diffraction
1.84Å resolution

Crystal Structure of Rat Protein Tyrosine Phosphatase eta Catalytic Domain

Released:
DOI: 10.2210/pdb3i36/pdb
PDB entry 3i36 coloured by chain, front view.
PDB entry 3i36 coloured by chain, side view.
PDB entry 3i36 coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Nascimento AS, Matozo HC, Santos MA, Polikarpov I

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178975 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
protein-tyrosine-phosphatase Chain: A
Molecule details ›
Chain: A
Length: 342 amino acids
Theoretical weight: 39.89 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q62884 (Residues: 875-1216; Coverage: 29%)
Gene name: Ptprj
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P212121
Unit cell:
a: 46.468Å b: 63.113Å c: 111.655Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.157 0.202
Expression system: Escherichia coli

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