X-ray diffraction
1.4Å resolution

Human SH3 domain of protein LASP1

Source organism: Homo sapiens
Entry authors: Siponen MI, Roos AK, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Karlberg T, Kotenyova T, Kotzsch A, Kragh Nielsen T, Moche M, Nyman T, Persson C, Sagemark J, Schueler H, Schutz P, Thorsell AG, Tresaugues L, Van Den Berg S, Weigelt J, Welin M, Wisniewska M, Nordlund P, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
LIM and SH3 domain protein 1 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q14847 (Residues: 202-261; Coverage: 23%)
Gene names: LASP1, MLN50
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P2
Unit cell:
a: 25.348Å b: 23.235Å c: 44.716Å
α: 90° β: 92.47° γ: 90°
R R work R free
0.203 0.202 0.222
Expression system: Escherichia coli