X-ray diffraction
1.9Å resolution

Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)

Source organism: Homo sapiens
Primary publication:
Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.
Proc. Natl. Acad. Sci. U.S.A. 106 11558-63 (2009)
PMID: 19556541

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Polycystin-2 Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 5.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q13563 (Residues: 833-872; Coverage: 4%)
Gene names: PKD2, TRPP2
Sequence domains: Ferredoxin I 4Fe-4S cluster domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P63
Unit cell:
a: 32.388Å b: 32.388Å c: 70.3Å
α: 90° β: 90° γ: 120°
R R work R free
0.217 0.194 0.227
Expression system: Escherichia coli