3hpm

X-ray diffraction
2.8Å resolution

Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2

Released:
Source organism: Rattus norvegicus
Primary publication:
Redox-regulated lipid membrane binding of the PICK1 PDZ domain.
Biochemistry 49 4432-9 (2010)
PMID: 20426484

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PRKCA-binding protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 111 amino acids
Theoretical weight: 11.53 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9EP80 (Residues: 19-110; Coverage: 22%)
Gene names: Pick1, Prkcabp
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 37.45Å b: 54Å c: 92.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.243 0.295
Expression system: Escherichia coli BL21(DE3)