PDBe 3hj2

X-ray diffraction
1.4Å resolution

Crystal structure of covalent dimer of HNP1

Released:
Source organism: Homo sapiens
Entry authors: Lubkowski J, Pazgier M, Lu W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 33 amino acids
Theoretical weight: 3.67 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P59665 (Residues: 65-94; Coverage: 40%)
Gene names: DEF1, DEFA1, DEFA1B, DEFA2, MRS
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21212
Unit cell:
a: 47.07Å b: 49.37Å c: 24.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.236
Expression system: Not provided