X-ray diffraction
2.15Å resolution

Crystal structure of human diamine oxidase in complex with the inhibitor pentamidine

Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Amiloride-sensitive amine oxidase [copper-containing] Chains: A, B
Molecule details ›
Chains: A, B
Length: 731 amino acids
Theoretical weight: 83.46 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
  • Canonical: P19801 (Residues: 21-751; Coverage: 100%)
Gene names: ABP1, AOC1, DAO1
Sequence domains:
Structure domains:

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 92.455Å b: 94.69Å c: 196.279Å
α: 90° β: 90° γ: 90°
R R work R free
0.184 0.182 0.221
Expression system: Drosophila melanogaster