X-ray diffraction
3.59Å resolution

The crystal structure of apo wild type CAP at 3.6 A resolution.

Source organism: Escherichia coli
Primary publication:
Structure of apo-CAP reveals that large conformational changes are necessary for DNA binding.
Proc. Natl. Acad. Sci. U.S.A. 106 16604-9 (2009)
PMID: 19805344

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
cAMP-activated global transcriptional regulator CRP Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 210 amino acids
Theoretical weight: 23.67 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli K-12
  • Canonical: P0ACJ8 (Residues: 1-210; Coverage: 100%)
Gene names: JW5702, b3357, cap, crp, csm
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3121
Unit cell:
a: 125.291Å b: 125.291Å c: 224.677Å
α: 90° β: 90° γ: 120°
R R work R free
0.296 0.295 0.318
Expression system: Escherichia coli K-12