3hid

X-ray diffraction
1.6Å resolution

Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92

Released:
Source organism: Yersinia pestis CO92
Entry authors: Zhang R, Zhou M, Peterson S, Anderson W, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed:
GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylosuccinate synthetase Chain: A
Molecule details ›
Chain: A
Length: 432 amino acids
Theoretical weight: 47.33 KDa
Source organism: Yersinia pestis CO92
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ZIV7 (Residues: 1-432; Coverage: 100%)
Gene names: YPO0378, YP_0534, purA, y0635
Sequence domains: Adenylosuccinate synthetase
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 68.903Å b: 68.903Å c: 199.166Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.16 0.198
Expression system: Escherichia coli