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Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 1.14.11.67: [Histone H3]-trimethyl-L-lysine(4) demethylase

Reaction catalysed:
(1a) a [histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine(4) + 2-oxoglutarate + O(2) = a [histone H3]-N(6),N(6)-dimethyl-L-lysine(4) + succinate + formaldehyde + CO(2)
Systematic name:
[Histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine(4),2-oxoglutarate:oxygen oxidoreductase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR019787
Domain description: Zinc finger, PHD-finger
Occurring in:
  1. Lysine-specific demethylase 5A
IPR011011
Domain description: Zinc finger, FYVE/PHD-type
Occurring in:
  1. Lysine-specific demethylase 5A
IPR001965
Domain description: Zinc finger, PHD-type
Occurring in:
  1. Lysine-specific demethylase 5A
IPR042803
Domain description: Transcription factor 19
Occurring in:
  1. Lysine-specific demethylase 5A
IPR047972
Domain description: Lysine-specific demethylase 5A, third PHD-finger
Occurring in:
  1. Lysine-specific demethylase 5A
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. Lysine-specific demethylase 5A

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