3gkz

X-ray diffraction
1.9Å resolution

Crystal structures of a therapeutic single chain antibody in complex methamphetamine

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
anti-methamphetamine single chain Fv Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 27.79 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21
Unit cell:
a: 34.338Å b: 65.265Å c: 48.513Å
α: 90° β: 98.75° γ: 90°
R-values:
R R work R free
0.21 0.21 0.235
Expression system: Komagataella pastoris