3giz

X-ray diffraction
2.2Å resolution

Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab fragment of anti-CD20 antibody Ofatumumab, light chain Chain: L
Molecule details ›
Chain: L
Length: 211 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins
Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 136.33Å b: 55.944Å c: 79.78Å
α: 90° β: 122.17° γ: 90°
R-values:
R R work R free
0.198 0.195 0.25
Expression system: Cricetulus griseus