3ggg

X-ray diffraction
2.21Å resolution

The crystal structure of A. aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prephenate/arogenate dehydrogenase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 314 amino acids
Theoretical weight: 35.26 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O67636 (Residues: 19-311; Coverage: 94%)
Gene names: aq_1755, tyrA
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 79.431Å b: 93.691Å c: 163.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.254
Expression system: Escherichia coli