X-ray diffraction
2.6Å resolution

Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2

Source organism: Homo sapiens
Entry authors: Chaikuad A, Hozjan V, Yue W, Cooper C, Elkins J, Pike ACW, Roos AK, Filippakopoulos P, von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
PDZ domain-containing protein GIPC2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 95 amino acids
Theoretical weight: 10.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8TF65 (Residues: 112-200; Coverage: 28%)
Gene name: GIPC2
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P4122
Unit cell:
a: 83.51Å b: 83.51Å c: 160.31Å
α: 90° β: 90° γ: 90°
R R work R free
0.225 0.223 0.265
Expression system: Escherichia coli