3gdk

X-ray diffraction
2Å resolution

Crystal structure of the orotidine 5'-monophosphate decarboxylase from Saccharomyces cerevisiae

Released:

Function and Biology Details

Reaction catalysed:
Orotidine 5'-phosphate = UMP + CO(2)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orotidine 5'-phosphate decarboxylase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 267 amino acids
Theoretical weight: 29.28 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P03962 (Residues: 1-267; Coverage: 100%)
Gene names: URA3, YEL021W
Sequence domains: Orotidine 5'-phosphate decarboxylase / HUMPS family
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 84.134Å b: 98.371Å c: 127.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.249 0.28
Expression system: Escherichia coli