X-ray diffraction
2.4Å resolution

Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen


Function and Biology Details

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
LRRNT domain-containing protein Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 170 amino acids
Theoretical weight: 18.72 KDa
Source organism: Petromyzon marinus
Expression system: Escherichia coli
  • Canonical: D0VX19 (Residues: 1-170; Coverage: 100%)
Gene name: vlr
Sequence domains:
Structure domains: Ribonuclease Inhibitor
Lysozyme C Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 62.874Å b: 106.244Å c: 218.544Å
α: 90° β: 90° γ: 90°
R R work R free
0.244 0.242 0.286
Expression system: Escherichia coli