3g2f

X-ray diffraction
2.35Å resolution

Crystal structure of the kinase domain of bone morphogenetic protein receptor type II (BMPR2) at 2.35 A resolution

Released:

Function and Biology Details

Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bone morphogenetic protein receptor type-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 336 amino acids
Theoretical weight: 38.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13873 (Residues: 189-517; Coverage: 33%)
Gene names: BMPR2, PPH1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 94.54Å b: 218.793Å c: 44.187Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.246
Expression system: Escherichia coli