3fzu

X-ray diffraction
2.5Å resolution

IgG1 Fab characterized by H/D exchange

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
immunoglobulin IgG1 Fab, light chain Chains: D, L
Molecule details ›
Chains: D, L
Length: 214 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
Structure domains: Immunoglobulins
immunoglobulin IgG1 Fab, heavy chain Chains: C, H
Molecule details ›
Chains: C, H
Length: 223 amino acids
Theoretical weight: 23.64 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2
Unit cell:
a: 243.051Å b: 61.938Å c: 100.846Å
α: 90° β: 113.94° γ: 90°
R-values:
R R work R free
0.213 0.21 0.261
Expression system: Mus musculus