X-ray diffraction
1.5Å resolution

NVGSNTY segment from Islet Amyloid Polypeptide (IAPP or Amylin), hydrated crystal form

Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo trimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Islet amyloid polypeptide Chain: A
Molecule details ›
Chain: A
Length: 7 amino acids
Theoretical weight: 754 Da
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P10997 (Residues: 64-70; Coverage: 10%)
Gene name: IAPP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 20.63Å b: 4.7Å c: 21.009Å
α: 90° β: 92.28° γ: 90°
R R work R free
0.149 0.148 0.158
Expression system: Not provided