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Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor

Source organism: Streptomyces coelicolor
Biochemical function: metal ion binding
Biological process: response to antibiotic
Cellular component: not assigned

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02909
Domain description: Tetracyclin repressor-like, C-terminal domain
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3fiw contains 4 copies of Pfam domain PF02909 (Tetracyclin repressor-like, C-terminal domain) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

PF00440
Domain description: Bacterial regulatory proteins, tetR family
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3fiw contains 4 copies of Pfam domain PF00440 (Bacterial regulatory proteins, tetR family) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003012
Domain description: Tetracycline transcriptional regulator, TetR
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR001647
Domain description: DNA-binding HTH domain, TetR-type
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR036271
Domain description: Tetracyclin repressor-like, C-terminal domain superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR004111
Domain description: Tetracycline repressor TetR, C-terminal
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR023772
Domain description: DNA-binding HTH domain, TetR-type, conserved site
Occurring in:
  1. HTH tetR-type domain-containing protein
IPR009057
Domain description: Homeobox-like domain superfamily
Occurring in:
  1. HTH tetR-type domain-containing protein

Structure domains

CATH CATH domains
1.10.357.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Tetracycline Repressor; domain 2
Homology: Tetracycline Repressor, domain 2
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3fiw contains 4 copies of CATH domain 1.10.357.10 (Tetracycline Repressor; domain 2) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.
1.10.10.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeodomain-like
Occurring in:
  1. HTH tetR-type domain-containing protein
The deposited structure of PDB entry 3fiw contains 4 copies of CATH domain 1.10.10.60 (Arc Repressor Mutant, subunit A) in HTH tetR-type domain-containing protein. Showing 1 copy in chain A.

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