X-ray diffraction
2Å resolution

Crystal structure of the death associated protein kinase in complex with AMPPNP and Mg2+

Source organism: Homo sapiens
Primary publication:
Structural insight into nucleotide recognition by human death-associated protein kinase.
Acta Crystallogr. D Biol. Crystallogr. 65 241-8 (2009)
PMID: 19237746

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Death-associated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 33.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P53355 (Residues: 1-285; Coverage: 20%)
Gene names: DAPK, DAPK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 46.669Å b: 62.461Å c: 88.599Å
α: 90° β: 90° γ: 90°
R R work R free
0.18 0.177 0.245
Expression system: Escherichia coli