X-ray diffraction
2.49Å resolution

Function and Biology Details

Reaction catalysed:
An acyl-[acyl-carrier protein] + NAD(+) = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Enoyl-acyl carrier protein reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 323 amino acids
Theoretical weight: 35.93 KDa
Source organism: Plasmodium berghei
Expression system: Escherichia coli
  • Canonical: Q6TEI5 (Residues: 75-396; Coverage: 86%)
Gene names: FABI, PBK173_000343000, PBNK65E_000333500, PBNK65NY_000333200, PBSP11A_000333500, PBSP11RLL_000333400
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

Cofactor: Ligand NAD 4 x NAD
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 64.339Å b: 121.2Å c: 87.832Å
α: 90° β: 108.97° γ: 90°
R R work R free
0.184 0.184 0.254
Expression system: Escherichia coli