Articles - 3f2a mentioned but not cited (4)
- The design and application of target-focused compound libraries. Harris CJ, Hill RD, Sheppard DW, Slater MJ, Stouten PF. Comb Chem High Throughput Screen 14 521-531 (2011)
- Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells. Andreoli M, Persico M, Kumar A, Orteca N, Kumar V, Pepe A, Mahalingam S, Alegria AE, Petrella L, Sevciunaite L, Camperchioli A, Mariani M, Di Dato A, Novellino E, Scambia G, Malhotra SV, Ferlini C, Fattorusso C. J Med Chem 57 7916-7932 (2014)
- Chemical space exploration based on recurrent neural networks: applications in discovering kinase inhibitors. Li X, Xu Y, Yao H, Lin K. J Cheminform 12 42 (2020)
- Novel Pan-Pim Kinase Inhibitors With Imidazopyridazine and Thiazolidinedione Structure Exert Potent Antitumor Activities. Sawaguchi Y, Yamazaki R, Nishiyama Y, Mae M, Abe A, Nishiyama H, Nishisaka F, Ibuki T, Sasai T, Matsuzaki T. Front Pharmacol 12 672536 (2021)
Reviews citing this publication (10)
- PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers. Brault L, Gasser C, Bracher F, Huber K, Knapp S, Schwaller J. Haematologica 95 1004-1015 (2010)
- Why target PIM1 for cancer diagnosis and treatment? Magnuson NS, Wang Z, Ding G, Reeves R. Future Oncol 6 1461-1478 (2010)
- The essential roles of chemistry in high-throughput screening triage. Dahlin JL, Walters MA. Future Med Chem 6 1265-1290 (2014)
- The PIM kinases in hematological cancers. Alvarado Y, Giles FJ, Swords RT. Expert Rev Hematol 5 81-96 (2012)
- Pim kinase inhibitors: a survey of the patent literature. Morwick T. Expert Opin Ther Pat 20 193-212 (2010)
- The oncogenic PIM kinase family regulates drug resistance through multiple mechanisms. Isaac M, Siu A, Jongstra J. Drug Resist Updat 14 203-211 (2011)
- Small molecule inhibitors of PIM1 kinase: July 2009 to February 2013 patent update. Arunesh GM, Shanthi E, Krishna MH, Sooriya Kumar J, Viswanadhan VN. Expert Opin Ther Pat 24 5-17 (2014)
- Targeting Pim kinases for cancer treatment: opportunities and challenges. Le BT, Kumarasiri M, Adams JR, Yu M, Milne R, Sykes MJ, Wang S. Future Med Chem 7 35-53 (2015)
- Insights from Pim1 structure for anti-cancer drug design. Ogawa N, Yuki H, Tanaka A. Expert Opin Drug Discov 7 1177-1192 (2012)
- Natural Products-Pyrazine Hybrids: A Review of Developments in Medicinal Chemistry. Chen GQ, Guo HY, Quan ZS, Shen QK, Li X, Luan T. Molecules 28 7440 (2023)
Articles citing this publication (23)
- Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion. Santio NM, Vahakoski RL, Rainio EM, Sandholm JA, Virtanen SS, Prudhomme M, Anizon F, Moreau P, Koskinen PJ. Mol Cancer 9 279 (2010)
- PIM1 kinase inhibitors induce radiosensitization in non-small cell lung cancer cells. Kim W, Youn H, Kwon T, Kang J, Kim E, Son B, Yang HJ, Jung Y, Youn B. Pharmacol Res 70 90-101 (2013)
- 7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. Huber K, Brault L, Fedorov O, Gasser C, Filippakopoulos P, Bullock AN, Fabbro D, Trappe J, Schwaller J, Knapp S, Bracher F. J Med Chem 55 403-413 (2012)
- The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Xiang Y, Hirth B, Asmussen G, Biemann HP, Bishop KA, Good A, Fitzgerald M, Gladysheva T, Jain A, Jancsics K, Liu J, Metz M, Papoulis A, Skerlj R, Stepp JD, Wei RR. Bioorg Med Chem Lett 21 3050-3056 (2011)
- Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors. Gustin DJ, Ma Z, Min X, Li Y, Hedberg C, Guimaraes C, Porter AC, Lindstrom M, Lester-Zeiner D, Xu G, Carlson TJ, Xiao S, Meleza C, Connors R, Wang Z, Kayser F. Bioorg Med Chem Lett 21 2492-2496 (2011)
- Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway. Ren K, Zhang W, Shi Y, Gong J. Pathol Oncol Res 16 229-237 (2010)
- Pim-2 phosphorylation of p21(Cip1/WAF1) enhances its stability and inhibits cell proliferation in HCT116 cells. Wang Z, Zhang Y, Gu JJ, Davitt C, Reeves R, Magnuson NS. Int J Biochem Cell Biol 42 1030-1038 (2010)
- Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles. Akué-Gédu R, Nauton L, Théry V, Bain J, Cohen P, Anizon F, Moreau P. Bioorg Med Chem 18 6865-6873 (2010)
- A novel Pim-1 kinase inhibitor targeting residues that bind the substrate peptide. Tsuganezawa K, Watanabe H, Parker L, Yuki H, Taruya S, Nakagawa Y, Kamei D, Mori M, Ogawa N, Tomabechi Y, Handa N, Honma T, Yokoyama S, Kojima H, Okabe T, Nagano T, Tanaka A. J Mol Biol 417 240-252 (2012)
- Insights into the Interaction Mechanisms of the Proviral Integration Site of Moloney Murine Leukemia Virus (Pim) Kinases with Pan-Pim Inhibitors PIM447 and AZD1208: A Molecular Dynamics Simulation and MM/GBSA Calculation Study. Chen Q, Wang Y, Shi S, Li K, Zhang L, Gao J. Int J Mol Sci 20 E5410 (2019)
- Synthesis and anticancer activity evaluation of 2(4-alkoxyphenyl)cyclopropyl hydrazides and triazolo phthalazines. De P, Baltas M, Lamoral-Theys D, Bruyère C, Kiss R, Bedos-Belval F, Saffon N. Bioorg Med Chem 18 2537-2548 (2010)
- Structure-based design of low-nanomolar PIM kinase inhibitors. Ishchenko A, Zhang L, Le Brazidec JY, Fan J, Chong JH, Hingway A, Raditsis A, Singh L, Elenbaas B, Hong VS, Marcotte D, Silvian L, Enyedy I, Chao J. Bioorg Med Chem Lett 25 474-480 (2015)
- A review on PIM kinases in tumors. Arrouchi H, Lakhlili W, Ibrahimi A. Bioinformation 15 40-45 (2019)
- Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors. Wurz RP, Sastri C, D'Amico DC, Herberich B, Jackson CLM, Pettus LH, Tasker AS, Wu B, Guerrero N, Lipford JR, Winston JT, Yang Y, Wang P, Nguyen Y, Andrews KL, Huang X, Lee MR, Mohr C, Zhang JD, Reid DL, Xu Y, Zhou Y, Wang HL. Bioorg Med Chem Lett 26 5580-5590 (2016)
- Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors. Wu B, Wang HL, Cee VJ, Lanman BA, Nixey T, Pettus L, Reed AB, Wurz RP, Guerrero N, Sastri C, Winston J, Lipford JR, Lee MR, Mohr C, Andrews KL, Tasker AS. Bioorg Med Chem Lett 25 775-780 (2015)
- The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors. Wurz RP, Pettus LH, Jackson C, Wu B, Wang HL, Herberich B, Cee V, Lanman BA, Reed AB, Chavez F, Nixey T, Laszlo J, Wang P, Nguyen Y, Sastri C, Guerrero N, Winston J, Lipford JR, Lee MR, Andrews KL, Mohr C, Xu Y, Zhou Y, Reid DL, Tasker AS. Bioorg Med Chem Lett 25 847-855 (2015)
- Understanding PIM-1 kinase inhibitor interactions with free energy simulation. Wang X, Sun Z. Phys Chem Chem Phys 21 7544-7558 (2019)
- Identification of quinones as novel PIM1 kinase inhibitors. Schroeder RL, Goyal N, Bratton M, Townley I, Pham NA, Tram P, Stone T, Geathers J, Nguyen K, Sridhar J. Bioorg Med Chem Lett 26 3187-3191 (2016)
- Computer aided drug design based on 3D-QSAR and molecular docking studies of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amine derivatives as PIM2 inhibitors: a proposal to chemists. Aouidate A, Ghaleb A, Ghamali M, Chtita S, Ousaa A, Choukrad M, Sbai A, Bouachrine M, Lakhlifi T. In Silico Pharmacol 6 5 (2018)
- Synthesis of new pyridothienopyrimidinone derivatives as Pim-1 inhibitors. Naguib BH, El-Nassan HB, Abdelghany TM. J Enzyme Inhib Med Chem 32 457-467 (2017)
- Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach. Shao M, Yuan Y, Yu K, Lei K, Zhu G, Chen L, Xiang M. Mol Divers 18 335-344 (2014)
- Structure-Based Virtual Screening and De Novo Design of PIM1 Inhibitors with Anticancer Activity from Natural Products. Park H, Jeon J, Kim K, Choi S, Hong S. Pharmaceuticals (Basel) 14 275 (2021)
- QSAR studies on PIM1 and PIM2 inhibitors using statistical methods: a rustic strategy to screen for 5-(1H-indol-5-yl)-1,3,4-thiadiazol analogues and predict their PIM inhibitory activity. Aouidate A, Ghaleb A, Ghamali M, Chtita S, Choukrad M, Sbai A, Bouachrine M, Lakhlifi T. Chem Cent J 11 41 (2017)