X-ray diffraction
1.76Å resolution

Crystal structure of MerB, the Organomercurial Lyase involved in a bacterial mercury resistance system


Function and Biology Details

Reaction catalysed:
An alkylmercury + H(+) = an alkane + Hg(2+)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Alkylmercury lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 212 amino acids
Theoretical weight: 23.06 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
  • Canonical: P77072 (Residues: 1-212; Coverage: 100%)
Gene name: merB
Sequence domains:
Structure domains: Beta-Lactamase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P21
Unit cell:
a: 38.71Å b: 89.947Å c: 52.167Å
α: 90° β: 100.53° γ: 90°
R R work R free
0.183 0.182 0.208
Expression system: Escherichia coli